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speak to your Health care provider about naloxone (brand name example: Narcan, Zimhi), a medicine you can continue hand or at your house for unexpected emergency therapy of the overdose. Concomitant use or discontinuation of CYP450 isoenzymes like CYP450 3A4 inducers, CYP450 3A4 inhibitors, or CYP450 2D6 inhibitors are sophisticated; concomitant u